The Oncotarget Success

Oncotarget is a peer-reviewed journal that focuses on the pathological basis of all cancer types, potential therapy targets as well as treatment protocols that are employed in order to enhance the management of individuals suffering from cancer. Oncotarget is also committed to the impact of new therapeutic agents, management programs and protocols on perspectives of patients such as adherence, life and also satisfaction. The medical journey which mostly focuses on Oncology also explores the evidence that is behind the existing and new therapies when it comes to enhancing outcomes. Oncotarget was launched in 2010 and is usually published by the Impact Journals.The Editors in Chief at Oncotarget are Mikhail Blagosklonny and Andrei Gudkov.

The two Editors in Chief also serve as scientists at the Roswell Park Cancer Institute. Oncotarget is a member of COPE (Committee on Publication Ethics) and also subscribes to the organization’s principles. The Journal Impact Factor of Oncotarget is currently 1.653 and is projected to be 2.612 by September 2017. Since its inception, the medical journal has managed to acquire a huge following which is international.  Oncotarget is normally abstracted also indexed in MEDLINE/PubMed, Science Citation Index Expanded, Scopus, Index Medicus and BIOSIS Previews. The rising popularity of Oncotarget has been attributed to its constructive, multiple peer-review, insightful and punctual approach.The medical journal has assisted its authors to enhance their research impact.

Following its success on oncology, Oncotarget has decided to now accept papers which are on topics other than oncology. The topics include Cell Biology, Endocrinology, Pharmacology and all its areas, Metabolism, Cardiology, Neuroscience and many others. Oncotarget as a term encompasses all cellular functions, pathways and molecules that are common in aging and cancer, microbes and cancer cells, neurons and lymphocytes as well as atherosclerosis and neurodegeneration. Oncotarget hopes to make results of science widely and rapidly available. It also seeks to make the impact maximum through its perceptive review.Through the leadership of prominent and skilled scientists, Oncotarget assists all scientific researchers in contributing to the science progress. The ultimate vision of the medical journal is to see people all over the world live a life without disease.

Talos Energy on the Gulf Coast

The Mexican government nationalized oil mining over 80 years ago and closed the oil and gas industry from private investment. The 1938 decision was reversed in an electoral vote back in 2012 to aid the ailing energy industry from the state-run monopoly of Petroleos Mexicanos. Immediately after, bids were made for companies and joint ventures to secure the right to explore the Zama-1 Well. A bid by three companies who intended to pursue the prospect as a joint venture sailed through. The three companies were;

Premier Oil Plc (based in London),

Talos Energy LLC (American and Houston-based),

And Mexican Sierra Oil and Gas.

The companies already had an agreement that described how they would split the costs and revenue shares. The Mexican company was entitled to 44 percent, the American company was entitled to 35 percent and the British company was entitled to 25 percent.

The commercial news world reacted boisterously to the new development of the lucrative oil prospecting contract on the Zama-1 Well. The Mexican government was also very firm in asserting that they would keenly follow the drilling to ensure that compliance would be upheld to protect the Mexican marine ecology. Such concerns were genuinely placed as the Zama-1 Well sits in the Sureste Basin. However, the fact that the oil well sits in the Sureste Basin also meant that the prospect had better geological chances of success because of the favorable structure of the basin.

The drilling expedition was estimated to take the three companies about 90 days to complete. According to tax reports, the joint venture had set aside over 16 million dollars for drilling alone. Talos energy and its partners estimate that the well holds about 200 to 500 barrels of crude oil.

Talos Energy LLC

Talos Energy is the winner of the 2013 WorkplaceDynamics’ Best Workplace among Local Small Businesses. It has always received praise from its main investor and regulator, Apollo Global Management, for having the most efficient and motivated employees in the American oil industry. It is a private company that focuses on prospecting for oil and acquiring oil properties in the Mexican Gulf and the Gulf Coast for exploitation. The company’s human resource department claims that it has an equity program where it allows its geologists and other specialist to share equity for any major oil discoveries that they make.


Clay Siegall follows dream, invents new class of cancer treatment drugs

Cancer treatment has traditionally entailed some of the most brutal regimes in medicine today. From radical surgery to radiation and chemotherapy, cancer treatment, since at least the 1930s, has been a torturous trial of endurance for any patient unlucky enough to receive a cancer diagnosis. Oftentimes, even the milder treatments, such as low dosage chemotherapies, will leave the patient with lasting deficits, such as neuropathy, dementia and other long-term neurological disorders.

However, there is a huge reward that has come with these terrible treatment. Cancer survival rates have increased dramatically over the last 70 years. Some cancers, which once were nearly always fatal, are now almost always curable, with five-year survival rates exceeding 99 percent. Prior to the 1930s, most diagnoses of cancer were tantamount to a death sentence. Few patients lived more than a couple of years.

Still, many types of cancer today do not have significantly better survival rates than they did 30 or 40 years ago. This is due largely to the fact that the three pillars of cancer treatment, surgery, radiation and chemotherapy essentially stopped getting better around the year 1960. While there have been certain improvements with some subtypes of cancer, many others have not seen any notable increases in survivability in the last 50 years.

But that began to change in the mid-1990s. Clay Siegall is one of the key players in developing the new class of drugs known as targeted cancer therapies. Most targeted therapies use the principle of targeting the malignancy directly, only releasing cytotoxic chemicals upon contact with the actual cancer cells. This reduces the worst side effects caused by chemotherapy, which is a medicinal blunt instrument, oftentimes releasing large amounts of poison directly into the bloodstream.

Aside from the near elimination of side effects, targeted cancer therapies are also able to dramatically increase the therapeutic window, allowing for much higher doses of cytotoxin and much more effective treatments.

Through his firm, Seattle Genetics, Dr. Siegall is continuing to develop this exciting new category of cancer treatment drugs, ensuring that the 21st century will see dramatic improvements in survivability of many subtypes of cancer.

OSI Industries Is A Simble Of American Success

OSI Industries opened its doors as a meat market in the early 1900s. It was founded by an immigrant named Otto Kolschowsky. Otto had a specific vision for his company. He named it Otto and Sons and proceeded to establish himself in the Chicago area. Over the years Otto adjusted his business model by providing service to food industries. This service included restaurants and supermarkets. Eventually Otto turned the business over to his sons and they continued the companies reputation of excellence.

As the 1950s approached, the McDonald’s Organization was expanding across the country. They were looking to establish themselves in Illinois and needed a meat supplier that they can trust. Otto and Sons was called upon to handle the task. Their relationship with the McDonald’s Organization blossomed over the years due to the many innovations that Otto and Sons brought to the meat manufacturing industry. They introduced cryogenic freezing chambers. This was a method of supplying large amounts of inventory without damaging it and delivering the product to McDonald’s in a workable fashion. Otto and Sons also introduced meat patty cutting machine, which catered to their most important client at the time.

Otto and Sons changed its name to OSI Industries and became the primary meat supplier to the McDonald’s Organization. OSI Industries expanded over the years to accommodate several other restaurant chains. Pizza Hut, Papa John’s Pizza, Starbucks and Subway are all clients of OSI Industries. The company has factories all over the world and operates with several different other food manufacturing companies. It allows OSI Industries to keep a diverse interest in food manufacturing, which helps them remain on cutting edge of industry.

OSI Industries acquired other companies such as Tyson Foods, Baho Foods and Flagship Food Group in order to expand its influence in a market that continues to grow.

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Evolution of AXA Advisor with Vincent Parascandola

Vincent Parascandola has led a lot of organization in achieving their objective and as well began much organization and accomplish more income. As an entrepreneur, he as well ensured that he develops AXA Advisor whereby they organization is the top French International Corporate. The organization is recognized because it offers more efficient security to prominent individuals and other top organization. His better managerial expert made to motivate workers in the organization to commit themselves to attending to clients wants efficiently. He as well likes to travel around the world to meet with proficient entrepreneur whereby they partner together in providing new creative techniques. Furthermore, Universal Insurance and Investment Management are the main services which they give to their clients hence enabling them to be safe in their financial statements. Also Vincent as the founder of AXA Advisor he was able to make the organization to be recognized globally due to their efficient services.

Vincent also ensured that more clients receive their services hence, therefore, he enlarged their services in other regions such as the North America, Asia –Pacific region, Africa and the Middle East and Western Europe. When the organization was established it was known as Mutuelle de L’assurance center L’incendie and then AXA Advisor in the year 1985. The organization also ensured they had they got the finest Swiss organization Winthur Group for €9 billion due to the better profits they made the organization is known for offering high-quality insurance services.

Vincent Parascandola as a philanthropist he was able to ensure that they support and establish AXA Research Fund and gave them €100 million whereby the money was to assist the center to do research which enables them to research to prevent the environment from hazardous happenings. The funding saw more than 256 research company funded for 3 years hence enabled the organization in helping the society all over the world. Vincent Parascandola ensured that he offers new techniques which will help the organization to improve and also as the Senior President ensure that they employ a specialized individual who will provide better services. He got his bachelor’s degree from Pace University.


Goettl Begins Making Things Better

The AZ Central report on Goettl knew what they were talking about when they said that Goettl used to struggle with the issues that they had. It was something that made it harder for the company to be able to continue succeeding but it was also something that set them up for success later on in their careers. Since Goettle knew that it was hard to do things in the beginning, they also knew what they needed to not do later on wihle they were creating opportunities for their clients. The number one thing that the company knew that they needed to change was the way that they handled their clients.

Customer service is important in any business but is especially important in the HVAC world because people want to be able to trust their contractors. Goettl did not have this from the beginning but they learned the right way to make the right kind of customer service choices and that led to them becoming one of the top HVAC companies in Phoenix and the surrounding areas. They were able to do this thanks to the opportunities that they had for their own lives and with their own things in the areas that they were in.

While Goettl has been working to make their customer service better, they are also doing everything that they can to improve the opportunities that they have for their clients. For Goettl, this means that they provide them with a great experience along with all of the other options that they need. They want to be able to make sure that all of the services that they offer are exactly what their clients need so they always make the choice to do this and provide this to their clients no matter what service they are hoping for.

Goettle is a premier HVAC company in Arizona. They have many different options for all of their clients and this has allowed them the chance to make sure that their clients are always being taken care of. It has allowed them to grow their business and has made things easier for them to try new things. Thanks to everything that Goettl has to offer their clients, they are confident in the ability that they have to treat them and to make sure that their clients are getting the best experience possible no matter what they want to have done.

Where Does WR Martavis Bryant Rank in Fantasy Football Rankings?

Last season was supposed to be a star-making year for Pittsburgh Steelers WR Martavis Bryant. In 2016, fantasy football rankings showed that fans believed he would make the jump from on-the-field player to a legitimate WR1 threat. And last season he showed some signs that he was becoming that 6’4”, 211 lb legit WR1 threat—that is, until he failed a second drug test and was suspended for the remainder of the season.

So, we must look back to 2014 and 2015 to see just where Martavis Bryant stands in 2017’s fantasy football rankings. During the 2014 season, Bryant was hampered by an A/C sprain and in 2015 was again kept off the field due to drug charges.

For Bryant to make an impact, he has to stay on the field! Whether it’s injuries or drugs, Bryant has missed 23 of the last 54 games.

Right now, fantasy football rankings have Martavis Bryant ranked around 30th in the wide receiver category.


George Soros continues to strengthen the world

George Soros is best known for being one of the Democrats’ top financial supporters. However, he has also become one of the leading philanthropists in the country. He has given away more than $12 billion dollars. His financial contributions have supported organizations and people who fight for freedom of expression, accountable government, fight for transparency and societies that defend justice and equality. Learn more about this article at

George Soros’ giving has targeted groups who have faced discrimination strictly for who they are. George Soros has supported Europe’s Roma people, drug users, sex workers and the LGBTI community. George Soros has faced intolerance firsthand.

George Soros was born in 1930 and survived the Nazi occupation of 1944-1945, which led to the murder of over 500,000 Hungarian Jews. Soros’ family survived by using fake identity documents, hiding their background and aiding others to do the same. According to Politico, George Soros later said “instead of submitting to our fate, we resisted an evil force that was much stronger than we were—yet we prevailed. Not only did we survive, but we managed to help others.”

George Soros left Hungary, as the communists were gathering up power in 1947. He traveled to London, where he gained employment as a railway porter and night-club waiter to finance his studies at the London School of Economics. In 1970, George Soros finally emigrated to the United States.

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George Soros then opened his own hedge fund, the Soros Fund Management, leading him to become one of the most successful investors in the history of the United States. Soros would use his funds to launch the Open Society Foundations. The OSF is a group of foundations, partners and projects in more than 100 countries. George Soros believes that societies can only flourish when they allow a democratic government to blossom, freedom of expression and respect individual rights.

George Soros became active in philanthropy in 1979, giving scholarships to those under apartheid. In the 1980s, George spoke out and defended the open exchange of ideas in the Communist Eastern Bloc. Following the fall of the Berlin Wall, George Soros created the Central European University, which was used as a place to stir up critical thinking. Following the Cold War, George Soros expanded his philanthropy work to the United States, Africa and Asia. He became one of the leading critics to attack the “war on drugs,” saying it is more harmful than helpful. Know more about George Soros on CNBC.

As George Soros gets older, he continues to take an active role in the work of Open Society Foundations, traveling across the globe, advocating for positive changes with global leaders both in private and in public. He has also become a strong supporter of organizations such as the Global Witness, the International Crisis Group, the European Council on Foreign Relations, and the Institute for New Economic Thinking.

End Citizens United Has HUGE First Quarter Fundraising Numbers

End Citizens United has a mission ahead of them and it may be one that is impossible to accomplish. Still, the team at End Citizens United are determined to make a difference in Washington D.C. when it comes to the problem of dark money pervading the world of politics. It is no secret that politicians are bought and paid for, at some level, by big money. You can see Republican Senators who receive millions of dollars in campaign funding from oil companies who will immediately go out and fight against clean energy for no other reason than a paycheck. Dark money is attacking the foundation of America and it may be up to End Citizens United to make the big difference.


End Citizens United is a political action committee that was founded in response to the 2010 Supreme Court Ruling which revolved around a conservative group by the name of Citizens United. Citizens United fought with the Supreme Court in order to loosen the strict financial regulations surrounding campaign financing. The results? The Supreme Court listened for some reason and now more and more politicians are being bought off, thus creating huge complications for Americans everywhere. Why would a politician stand behind their constituents if they get a check from a big oil company?


Tiffany Muller points to the election of Donald Trump in 2016 as a turning point in the work of her PAC. End Citizens United has seen an unprecedented raise in terms of donations and activity since Trump’s election and the reasons are pretty clear: people are furious that an unqualified big spender could get elected. President Trump has continued to blaze the destructive path of big money by hiring lobbyists at every level to work within the White House. Muller and her supporters at End Citizens United know that the very basic tenets of a free government are at stake here and that has given some sense of urgency to her task.


End Citizens United has seen record breaking donations over the first quarter of 2017 and those numbers are expected to continue rising. Through the first quarter of the fiscal year the team at End Citizens United saw over 100,000 donations pour into the PAC. Of those 100,000 donations, nearly half of them were from first time supporter. Having a huge influx of first time supporters is absolutely integral to a long living and successful PAC.


With supporters coming out in huge numbers Muller knows that it is time for her PAC to really get to work. End Citizens United has gone on to endorse 11 top Democrats who are all ready and willing to push the fight against Citizens United ahead of the 2018 Congressional Elections.


Rocketship Schools Allow Parents to Interview Teachers Before Hiring

Rocketship schools which have gained notorious attention nationwide for their high student scores from the opening year in 2007 and have since opened schools across the US despite being based and founded in California. The school also has a unique policy of allowing parents to help interview teachers and provide input on who should be hired to teach their children. If you think about it, it really does make sense. These parents are sending children to these schools to allow them to have some sort of say in the programs that go on there and who is doing the teaching only makes sense.

Preston Smith who is the CEO of the Rocketship schools believes this is not a rare phenomenon and that it should be common practice at all schools around the country. The school either has the teacher interviewed by 3-6 selected parents who undergo training to help do panel interviews on teachers and others hold “town hall” style meetings that allow many parents to meet teachers and ask questions of them before providing input on if they feel that teacher should be able to teach their child.

These meetings are only done once finalist candidates are selected for teaching roles.

This can work out well for everyone in several ways. The parents feel better knowing who will be working with their children and will be able to defy if this is where they want their children to go to learn. Sometimes, teachers can also get a feel if the parents and the population of the school are the right fit for them far as teaching will go. Everyone gets to know each other and that helps everyone understand what they are getting into in the first place.

One teacher has decided she is not ready for the high levels of interactions with the parents so she walks out and decides this job is not for her. It helped a teacher make a right choice. The feedback parents provide the school will also really help the school choose teachers that provide the students with the best education that align with their upbringing and family views than they would if parents were not involved in that process. Parents site loving this idea that the school allows them to decide who is going to interact with their children and to provide them with a sense of what their child will be learning and who their role models will be.